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Cady, Sarah D., Schmidt-Rohr, Klaus, Wang, Jun, Soto, Cinque S., DeGrado, William F., Hong, Mei (2010) Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature, 463 (7281). 689-692 doi:10.1038/nature08722

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Reference TypeJournal (article/letter/editorial)
TitleStructure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
JournalNature
AuthorsCady, Sarah D.Author
Schmidt-Rohr, KlausAuthor
Wang, JunAuthor
Soto, Cinque S.Author
DeGrado, William F.Author
Hong, MeiAuthor
Year2010 (February)Volume463
Issue7281
PublisherSpringer Science and Business Media LLC
DOIdoi:10.1038/nature08722Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID2998321Long-form Identifiermindat:1:5:2998321:2
GUID0
Full ReferenceCady, Sarah D., Schmidt-Rohr, Klaus, Wang, Jun, Soto, Cinque S., DeGrado, William F., Hong, Mei (2010) Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature, 463 (7281). 689-692 doi:10.1038/nature08722
Plain TextCady, Sarah D., Schmidt-Rohr, Klaus, Wang, Jun, Soto, Cinque S., DeGrado, William F., Hong, Mei (2010) Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature, 463 (7281). 689-692 doi:10.1038/nature08722
In(2010, February) Nature Vol. 463 (7281) Springer Science and Business Media LLC

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Cady, Sarah D., Mishanina, Tatiana V., Hong, Mei (2009) Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding. Journal of Molecular Biology, 385 (4). 1127-1141 doi:10.1016/j.jmb.2008.11.022
Cady, Sarah D., Wang, Jun, Wu, Yibing, DeGrado, William F., Hong, Mei (2011) Specific Binding of Adamantane Drugs and Direction of Their Polar Amines in the Pore of the Influenza M2 Transmembrane Domain in Lipid Bilayers and Dodecylphosphocholine Micelles Determined by NMR Spectroscopy. Journal Of The American Chemical Society, 133 (12) 4274-4284 doi:10.1021/ja102581n
Wang, Jun, Cady, Sarah D., Balannik, Victoria, Pinto, Lawrence H., DeGrado, William F., Hong, Mei (2009) Discovery of Spiro-Piperidine Inhibitors and Their Modulation of the Dynamics of the M2 Proton Channel from Influenza A Virus. Journal Of The American Chemical Society, 131 (23) 8066-8076 doi:10.1021/ja900063s
Cady, S. D., Hong, M. (2008) Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel. Proceedings of the National Academy of Sciences, 105 (5) 1483-1488 doi:10.1073/pnas.0711500105
Stouffer, Amanda L., Acharya, Rudresh, Salom, David, Levine, Anna S., Di Costanzo, Luigi, Soto, Cinque S., Tereshko, Valentina, Nanda, Vikas, Stayrook, Steven, DeGrado, William F. (2008) Structural basis for the function and inhibition of an influenza virus proton channel. Nature, 451 (7178). 596-599 doi:10.1038/nature06528
Stouffer, Amanda L., Acharya, Rudresh, Salom, David, Levine, Anna S., Di Costanzo, Luigi, Soto, Cinque S., Tereshko, Valentina, Nanda, Vikas, Stayrook, Steven, DeGrado, William F. (2008) Erratum: Structural basis for the function and inhibition of an influenza virus proton channel. Nature, 452 (7185). 380 doi:10.1038/nature06845
Cady, Sarah, Wang, Tuo, Hong, Mei (2011) Membrane-Dependent Effects of a Cytoplasmic Helix on the Structure and Drug Binding of the Influenza Virus M2 Protein. Journal Of The American Chemical Society, 133 (30) 11572-11579 doi:10.1021/ja202051n
Mandala, Venkata S., Liao, Shu-Yu, Gelenter, Martin D., Hong, Mei (2019) The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers. Scientific Reports, 9. doi:10.1038/s41598-019-40217-1
Thomaston, Jessica L., DeGrado, William F. (2017) X-ray crystal structures of the influenza A M2 proton channel bound to amantadine, rimantadine and inhibiting compounds. Acta Crystallographica Section A Foundations and Advances, 73. doi:10.1107/s0108767317099226
Williams, Jonathan K., Tietze, Daniel, Wang, Jun, Wu, Yibing, DeGrado, William F., Hong, Mei (2013) Drug-Induced Conformational and Dynamical Changes of the S31N Mutant of the Influenza M2 Proton Channel Investigated by Solid-State NMR. Journal Of The American Chemical Society, 135 (26) 9885-9897 doi:10.1021/ja4041412
Liang, Ruibin, Swanson, Jessica M. J., Madsen, Jesper J., Hong, Mei, DeGrado, William F., Voth, Gregory A. (2016) Acid activation mechanism of the influenza A M2 proton channel. Proceedings of the National Academy of Sciences, 113 (45) doi:10.1073/pnas.1615471113
 
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