Shalem, Ophir, Sanjana, Neville E., Hartenian, Ella, Shi, Xi, Scott, David A., Mikkelsen, Tarjei S., Heckl, Dirk, Ebert, Benjamin L., Root, David E., Doench, John G., Zhang, Feng (2014) Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells. Science, 343 (6166). 84-87 doi:10.1126/science.1247005

See Also

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	Sanjana, Neville E, Shalem, Ophir, Zhang, Feng (2014) Improved vectors and genome-wide libraries for CRISPR screening. Nature Methods, 11 (8). 783-784 doi:10.1038/nmeth.3047
	Wang, Tim, Wei, Jenny J., Sabatini, David M., Lander, Eric S. (2014) Genetic Screens in Human Cells Using the CRISPR-Cas9 System. Science, 343 (6166). 80-84 doi:10.1126/science.1246981
	Ran, F. Ann, Cong, Le, Yan, Winston X., Scott, David A., Gootenberg, Jonathan S., Kriz, Andrea J., Zetsche, Bernd, Shalem, Ophir, Wu, Xuebing, Makarova, Kira S., Koonin, Eugene V., Sharp, Phillip A., Zhang, Feng (2015) In vivo genome editing using Staphylococcus aureus Cas9. Nature, 520 (7546). 186-191 doi:10.1038/nature14299
	Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Sanjana, Neville E., Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Zhang, Feng, Orkin, Stuart H., Bauer, Daniel E. (2015) BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature, 527 (7577). 192-197 doi:10.1038/nature15521
	Sanson, Kendall R., Hanna, Ruth E., Hegde, Mudra, Donovan, Katherine F., Strand, Christine, Sullender, Meagan E., Vaimberg, Emma W., Goodale, Amy, Root, David E., Piccioni, Federica, Doench, John G. (2018) Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities. Nature Communications, 9. doi:10.1038/s41467-018-07901-8
	Ting, Pamela Y., Parker, Albert E., Lee, J. Scott, Trussell, Chris, Sharif, Orzala, Luna, Fabio, Federe, Glenn, Barnes, S. Whitney, Walker, John R., Vance, Julie, Gao, Mu-Yun, Klock, Heath E., Clarkson, Scott, Russ, Carsten, Miraglia, Loren J., Cooke, Michael P., Boitano, Anthony E., McNamara, Peter, Lamb, John, Schmedt, Christian, Snead, Jennifer L. (2018) Guide Swap enables genome-scale pooled CRISPR–Cas9 screening in human primary cells. Nature Methods, 15 (11). 941-946 doi:10.1038/s41592-018-0149-1
	Erb, Michael A., Scott, Thomas G., Li, Bin E., Xie, Huafeng, Paulk, Joshiawa, Seo, Hyuk-Soo, Souza, Amanda, Roberts, Justin M., Dastjerdi, Shiva, Buckley, Dennis L., Sanjana, Neville E., Shalem, Ophir, Nabet, Behnam, Zeid, Rhamy, Offei-Addo, Nana K., Dhe-Paganon, Sirano, Zhang, Feng, Orkin, Stuart H., Winter, Georg E., Bradner, James E. (2017) Transcription control by the ENL YEATS domain in acute leukaemia. Nature, 543 (7644). 270-274 doi:10.1038/nature21688
	(2014) Improving Whole-Genome Screens. Science, 343 (6166). 5 doi:10.1126/science.343.6166.5-f
	Meissner, Alexander, Mikkelsen, Tarjei S., Gu, Hongcang, Wernig, Marius, Hanna, Jacob, Sivachenko, Andrey, Zhang, Xiaolan, Bernstein, Bradley E., Nusbaum, Chad, Jaffe, David B., Gnirke, Andreas, Jaenisch, Rudolf, Lander, Eric S. (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature, 454 (7205). 766-770 doi:10.1038/nature07107
	Grant, Corena V., Cai, Shengxin, Risinger, April L., Liang, Huiyun, O’Keefe, Barry R., Doench, John G., Cichewicz, Robert H., Mooberry, Susan L. (2020) CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells. Journal of Natural Products, 83 (10) 3080-3092 doi:10.1021/acs.jnatprod.0c00642
	(2014) Counteracting Cannabis. Science, 343 (6166). 5 doi:10.1126/science.343.6166.5-e