Amountzias, Vaios; Gikas, Evagelos; Aligiannis, Nektarios (2025) PLANTA Protocol for the Direct Detection and Identification of Bioactive Compounds in Complex Mixtures via Combined NMR-HPTLC-Based Heterocovariance. Analytical Chemistry, 97 (40). doi:10.1021/acs.analchem.5c02192

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	Newman, David J., Cragg, Gordon M., Snader, Kenneth M. (2003) Natural Products as Sources of New Drugs over the Period 1981−2002. Journal of Natural Products, 66. 1022-1037 doi:10.1021/np030096l
	Not Yet Imported: - book-chapter : 10.1016/bs.armc.2023.10.001 If you would like this item imported into the Digital Library, please contact us quoting Book ID 9780443137099
	Newman, David J., Cragg, Gordon M. (2020) Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019. Journal of Natural Products, 83. 770-803 doi:10.1021/acs.jnatprod.9b01285
	Domingo-Fernández, Daniel, Gadiya, Yojana, Preto, António José, Krettler, Christoph A., Mubeen, Sarah, Allen, August, Healey, David, Colluru, Viswa (2024) Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process. Journal of Natural Products, 87 (7) 1844-1851 doi:10.1021/acs.jnatprod.4c00581
	Not Yet Imported: - journal-article : 10.1038/s41573-020-00114-z If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: Journal of Ethnopharmacology - journal-article : 10.1016/j.jep.2005.05.029 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Bucar, Franz, Wube, Abraham, Schmid, Martin (2013) Natural product isolation – how to get from biological material to pure compounds. Natural Product Reports, 30 (4). 525pp. doi:10.1039/c3np20106f
	Not Yet Imported: - journal-article : 10.3892/br.2017.909 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1016/j.chroma.2014.10.091 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Wolfender, Jean-Luc, Nuzillard, Jean-Marc, van der Hooft, Justin J. J., Renault, Jean-Hugues, Bertrand, Samuel (2019) Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography–High-Resolution Tandem Mass Spectrometry and NMR Profiling,in SilicoDatabases, and Chemometrics. Analytical Chemistry, 91 (1). 704-742 doi:10.1021/acs.analchem.8b05112
	Wolfender, Jean-Luc, Litaudon, Marc, Touboul, David, Queiroz, Emerson Ferreira (2019) Innovative omics-based approaches for prioritisation and targeted isolation of natural products – new strategies for drug discovery. Natural Product Reports, 36 (6). 855-868 doi:10.1039/c9np00004f
	Beniddir, Mehdi A., Kang, Kyo Bin, Genta-Jouve, Grégory, Huber, Florian, Rogers, Simon, van der Hooft, Justin J. J. (2021) Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches. Natural Product Reports, 38 (11) 1967-1993 doi:10.1039/d1np00023c
	Not Yet Imported: - journal-article : 10.1021/acschembio.7b00413 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Nothias, Louis-Félix, Nothias-Esposito, Mélissa, da Silva, Ricardo, Wang, Mingxun, Protsyuk, Ivan, Zhang, Zheng, Sarvepalli, Abi, Leyssen, Pieter, Touboul, David, Costa, Jean, Paolini, Julien, Alexandrov, Theodore, Litaudon, Marc, Dorrestein, Pieter C. (2018) Bioactivity-Based Molecular Networking for the Discovery of Drug Leads in Natural Product Bioassay-Guided Fractionation. Journal of Natural Products, 81. 758-767 doi:10.1021/acs.jnatprod.7b00737
	Ory, Lucie, Nazih, El-Hassane, Daoud, Sahar, Mocquard, Julia, Bourjot, Mélanie, Margueritte, Laure, Delsuc, Marc-André, Bard, Jean-Marie, Pouchus, Yves François, Bertrand, Samuel, Roullier, Catherine (2019) Targeting bioactive compounds in natural extracts - Development of a comprehensive workflow combining chemical and biological data. Analytica Chimica Acta, 1070. 29-42 doi:10.1016/j.aca.2019.04.038
	Not Yet Imported: ACS Central Science - journal-article : 10.1021/acscentsci.1c01108 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1080/10408347.2021.1873100 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.3390/molecules25215128 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: Current Opinion in Biotechnology - journal-article : 10.1016/j.copbio.2013.08.004 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1002/slct.201600744 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Amountzias, Vaios, Cheilari, Antigoni, Vontzalidou, Argyro, Benaki, Dimitra, Gikas, Evagelos, Aligiannis, Nektarios (2024) Can NMR-HetCA be a Reliable Prediction Tool for the Direct Identification of Bioactive Substances in Complex Mixtures? Analytical Chemistry, 96 (50). doi:10.1021/acs.analchem.4c05080
	Cloarec, Olivier, Dumas, Marc-Emmanuel, Craig, Andrew, Barton, Richard H., Trygg, Johan, Hudson, Jane, Blancher, Christine, Gauguier, Dominique, Lindon, John C., Holmes, Elaine, Nicholson, Jeremy (2005) Statistical Total Correlation Spectroscopy:  An Exploratory Approach for Latent Biomarker Identification from Metabolic1H NMR Data Sets. Analytical Chemistry, 77 (5). 1282-1289 doi:10.1021/ac048630x
	Crockford, Derek J., Holmes, Elaine, Lindon, John C., Plumb, Robert S., Zirah, Severine, Bruce, Stephen J., Rainville, Paul, Stumpf, Chris L., Nicholson, Jeremy K. (2006) Statistical Heterospectroscopy, an Approach to the Integrated Analysis of NMR and UPLC-MS Data Sets:  Application in Metabonomic Toxicology Studies. Analytical Chemistry, 78 (2). 363-371 doi:10.1021/ac051444m
	Not Yet Imported: - journal-article : 10.1016/j.pnmrs.2020.09.001 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: Phytochemical Analysis - journal-article : 10.1002/pca.3178 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1016/j.phytol.2017.03.001 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1016/j.jep.2018.10.008 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Grienke, Ulrike, Foster, Paul A., Zwirchmayr, Julia, Tahir, Ammar, Rollinger, Judith M., Mikros, Emmanuel (2019) 1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues. Scientific Reports, 9. doi:10.1038/s41598-019-47434-8
	Not Yet Imported: - journal-article : 10.3390/biom10050679 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Langeder, Julia, Döring, Kristin, Schmietendorf, Hannes, Grienke, Ulrike, Schmidtke, Michaela, Rollinger, Judith M. (2023) 1H NMR-Based Biochemometric Analysis of Morus alba Extracts toward a Multipotent Herbal Anti-Infective. Journal of Natural Products, 86 (1) 8-17 doi:10.1021/acs.jnatprod.2c00481
	Not Yet Imported: - book : 10.1007/978-3-642-10729-0 If you would like this item imported into the Digital Library, please contact us quoting Book ID 9783642107276
	Not Yet Imported: - journal-article : 10.1080/10826076.2020.1725548 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1080/10408347.2020.1797467 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Morlock, Gertrud E. (2021) High-performance thin-layer chromatography combined with effect-directed assays and high-resolution mass spectrometry as an emerging hyphenated technology: A tutorial review. Analytica Chimica Acta, 1180. 338644pp. doi:10.1016/j.aca.2021.338644
	Fichou, Dimitri, Morlock, Gertrud E. (2018) Powerful Artificial Neural Network for Planar Chromatographic Image Evaluation, Shown for Denoising and Feature Extraction. Analytical Chemistry, 90 (11). 6984-6991 doi:10.1021/acs.analchem.8b01298
	Fichou, Dimitri, Ristivojević, Petar, Morlock, Gertrud E. (2016) Proof-of-Principle of rTLC, an Open-Source Software Developed for Image Evaluation and Multivariate Analysis of Planar Chromatograms. Analytical Chemistry, 88 (24). 12494-12501 doi:10.1021/acs.analchem.6b04017
	Wadie, Mina, Abdel-Moety, Ezzat M., Rezk, Mamdouh R., Marzouk, Hoda M. (2023) A novel smartphone HPTLC assaying platform versus traditional densitometric method for simultaneous quantification of alfuzosin and solifenacin in their dosage forms as well as monitoring content uniformity and drug residues on the manufacturing equipment. RSC Advances, 13 (17) 11642-11651 doi:10.1039/d3ra01211e
	Sing, Lucas, Schwack, Wolfgang, Göttsche, Rieke, Morlock, Gertrud Elisabeth (2022) 2LabsToGo─Recipe for Building Your Own Chromatography Equipment Including Biological Assay and Effect Detection. Analytical Chemistry, 94 (42) 14554-14564 doi:10.1021/acs.analchem.2c02339
	Not Yet Imported: Bioanalytical Reviews - journal-article : 10.1007/s12566-010-0019-5 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1002/pca.2670 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
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	Not Yet Imported: - journal-article : 10.1016/j.jphotobiol.2016.03.004 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - monograph : 10.1055/b-002-66241 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.3390/molecules27196651 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1007/s11696-021-01902-6 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: - journal-article : 10.1016/j.neuint.2005.10.010 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Not Yet Imported: Innovative Food Science & Emerging Technologies - journal-article : 10.1016/j.ifset.2005.09.001 If you would like this item imported into the Digital Library, please contact us quoting Journal ID
	Cody, Robert B., Laramée, James A., Durst, H. Dupont (2005) Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions. Analytical Chemistry, 77 (8). 2297-2302 doi:10.1021/ac050162j
	Not Yet Imported: Open Chemistry - journal-article : 10.2478/s11532-012-0025-2 If you would like this item imported into the Digital Library, please contact us quoting Journal ID

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