Sharma, Sejal, Nozohouri, Saeideh, Vaidya, Bhuvaneshwar, Abbruscato, Thomas (2021) Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke. Life Sciences, 274. 119343pp. doi:10.1016/j.lfs.2021.119343

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Reference Type	Journal (article/letter/editorial)
Title	Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke
Journal	Life Sciences
Authors	Sharma, Sejal		Author
	Nozohouri, Saeideh		Author
	Vaidya, Bhuvaneshwar		Author
	Abbruscato, Thomas		Author
Year	2021 (June)	Volume	274
Publisher	Elsevier BV
DOI	doi:10.1016/j.lfs.2021.119343Search in ResearchGate
	Generate Citation Formats
Mindat Ref. ID	13601889	Long-form Identifier	mindat:1:5:13601889:8
GUID	0
Full Reference	Sharma, Sejal, Nozohouri, Saeideh, Vaidya, Bhuvaneshwar, Abbruscato, Thomas (2021) Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke. Life Sciences, 274. 119343pp. doi:10.1016/j.lfs.2021.119343
Plain Text	Sharma, Sejal, Nozohouri, Saeideh, Vaidya, Bhuvaneshwar, Abbruscato, Thomas (2021) Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke. Life Sciences, 274. 119343pp. doi:10.1016/j.lfs.2021.119343
In	(2021) Life Sciences Vol. 274. Elsevier BV

	Sifat, Ali Ehsan, Nozohouri, Saeideh, Archie, Sabrina Rahman, Chowdhury, Ekram Ahmed, Abbruscato, Thomas J. (2022) Brain Energy Metabolism in Ischemic Stroke: Effects of Smoking and Diabetes. International Journal of Molecular Sciences, 23 (15) 8512 doi:10.3390/ijms23158512
	*Qaisar, Rizwan (2023) Targeting neuromuscular junction to treat neuromuscular disorders. Life Sciences, 333. 122186 doi:10.1016/j.lfs.2023.122186*
	Yang, Jenq-Lin, Yang, Yun-Ru, Chen, Shang-Der (2019) The potential of drug repurposing combined with reperfusion therapy in cerebral ischemic stroke: A supplementary strategy to endovascular thrombectomy. Life Sciences, 236. 116889pp. doi:10.1016/j.lfs.2019.116889
	*Recabarren, Daniela, Alarcón, Marcelo (2017) Gene networks in neurodegenerative disorders. Life Sciences, 183. 83-97 doi:10.1016/j.lfs.2017.06.009*
	Elfawy, Hasnaa A., Das, Biswadeep (2019) Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies. Life Sciences, 218. 165-184 doi:10.1016/j.lfs.2018.12.029
	Zangerolamo, Lucas, Vettorazzi, Jean F., Rosa, Lucas R.O., Carneiro, Everardo M., Barbosa, Helena C.L. (2021) The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sciences, 272. 119252pp. doi:10.1016/j.lfs.2021.119252
	Zhang, Luyun, Wang, Jianxin, Rong, Shaoya, Dong, Hui (2025) Elucidating novel mechanism of action of spiperone for drug repurposing to prevent and treat murine colitis and sepsis. Life Sciences, 361. doi:10.1016/j.lfs.2024.123268
	Srinivasan, Krishnamoorthy, Sharma, Shyam S. (2012) 3-Bromo-7-nitroindazole attenuates brain ischemic injury in diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP. Life Sciences, 90 (3) 154-160 doi:10.1016/j.lfs.2011.10.017
	Papini, Nadia, Giussani, Paola, Tringali, Cristina (2024) Metformin Lysosomal Targeting: A Novel Aspect to Be Investigated for Metformin Repurposing in Neurodegenerative Diseases?. International Journal of Molecular Sciences, 25 (16) 8884 doi:10.3390/ijms25168884
	Asveda, Thankavelu, Talwar, Priti, Ravanan, Palaniyandi (2023) Exploring microglia and their phenomenal concatenation of stress responses in neurodegenerative disorders. Life Sciences, 328. 121920 doi:10.1016/j.lfs.2023.121920
	Sharma, Archana, Ahmad, Shaniya, Ahmad, Tanveer, Ali, Shakir, Syed, Mansoor Ali (2021) Mitochondrial dynamics and mitophagy in lung disorders. Life Sciences, 284. 119876pp. doi:10.1016/j.lfs.2021.119876

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Sharma, Sejal, Nozohouri, Saeideh, Vaidya, Bhuvaneshwar, Abbruscato, Thomas (2021) Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke. Life Sciences, 274. 119343pp. doi:10.1016/j.lfs.2021.119343

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