Sayed, Ahmed M., Hassanein, Emad H.M., Ali, Fares E.M., Omar, Zainab M.M., Rashwan, Eman K., Mohammedsaleh, Zuhair M., Abd El-Ghafar, Omnia A.M. (2021) Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological analysis. Life Sciences, 284. 119911pp. doi:10.1016/j.lfs.2021.119911

See Also

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	Ali, Fares E.M., Sayed, Ahmed M., El-Bahrawy, Ali H., Omar, Zainab M.M., Hassanein, Emad H.M. (2021) Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity. Life Sciences, 275. 119349pp. doi:10.1016/j.lfs.2021.119349
	Hassanein, Emad H.M., Althagafy, Hanan S., Atwa, Ahmed M., Kozman, Magy R., Kotb El-Sayed, Mohamed.I., Soubh, Ayman A. (2022) Taurine attenuated methotrexate-induced intestinal injury by regulating NF-κB/iNOS and Keap1/Nrf2/HO-1 signals. Life Sciences, 311. 121180 doi:10.1016/j.lfs.2022.121180
	Bakr, Adel G., Hassanein, Emad H.M., Ali, Fares E.M., El-Shoura, Ehab A.M. (2022) Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways. Life Sciences, 311. 121152 doi:10.1016/j.lfs.2022.121152
	Hassanein, Emad H.M., Kamel, Esam Omar, Ali, Fares E.M., Ahmed, Marwa Abdel-Raheim (2021) Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways. Life Sciences, 281. 119754pp. doi:10.1016/j.lfs.2021.119754
	Ali, Fares E.M., Hassanein, Emad H.M., Bakr, Adel G., El-Shoura, Ehab A.M., El-Gamal, Dalia A., Mahmoud, Amany R., Abd-Elhamid, Tarek Hamdy (2020) Ursodeoxycholic acid abrogates gentamicin-induced hepatotoxicity in rats: Role of NF-κB-p65/TNF-α, Bax/Bcl-xl/Caspase-3, and eNOS/iNOS pathways. Life Sciences, 254. 117760pp. doi:10.1016/j.lfs.2020.117760
	Bakr, Adel G.; Hassanein, Emad H.M.; Ali, Fares E.M.; El-Shoura, Ehab A.M. (2025) Retraction notice to “Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways” [Life Sci. 311 (2022) 121152]. Life Sciences, 380. doi:10.1016/j.lfs.2025.123963
	Mahmoud, Ayman M., Abd El-Ghafar, Omnia A.M., Alzoghaibi, Mohammed A., Hassanein, Emad H.M. (2021) Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1. Life Sciences, 278. 119600pp. doi:10.1016/j.lfs.2021.119600
	Mahmoud, Nahed A., Hassanein, Emad H.M., Bakhite, Etify A., Shaltout, Eman S., Sayed, Ahmed M. (2023) Apocynin and its chitosan nanoparticles attenuated cisplatin-induced multiorgan failure: Synthesis, characterization, and biological evaluation. Life Sciences, 314. 121313 doi:10.1016/j.lfs.2022.121313
	Ali, Fares E.M., M. Elfiky, Mohamed, Fadda, Walaa A., Ali, Howaida S., Mahmoud, Amany Refaat, Mohammedsaleh, Zuhair M., Abd-Elhamid, Tarek Hamdy (2021) Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight. Life Sciences, 276. 119433pp. doi:10.1016/j.lfs.2021.119433
	Hassanein, Emad H.M., Mohamed, Wafaa R., Ahmed, Osama S., Abdel-Daim, Mohamed M., Sayed, Ahmed M. (2022) The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view. Life Sciences, 308. 120971 doi:10.1016/j.lfs.2022.120971
	Ali, Fares E.M., Abdel-Reheim, Mustafa Ahmed, Hassanein, Emad H.M., Abd El-Aziz, Mostafa K., Althagafy, Hanan S., Badran, Khalid S.A. (2024) Exploring the potential of drug repurposing for liver diseases: A comprehensive study. Life Sciences, 347. 122642 doi:10.1016/j.lfs.2024.122642